Saito Lab, Kitasato University, AIST & The University of Tokyo

Saito Lab, Kitasato University, AIST & The University of Tokyo

Saito Lab, Kitasato University, AIST & The University of Tokyo

japanese

Bioinformatics for Bioengineering

We seek to reveal the principles of life through large-scale data analysis based on machine-learning and bioinformatics approaches, and to use these rules for designing and controlling biomolecules. We are also interested in laboratory automation using experiment robots.

Topics

Recruiting graduate students! [Join us]

  • 2024.01.04
    Our paper "Extensive antibody search with whole spectrum black-box optimization" was accepted in Scientific Reports. [Journal Link]
  • 2024.01.04
    Adrien Mialland (postdoc researcher, AIST) joined our lab. [Member]
  • 2023.11.20
    Our paper "VeloPro: A pipeline integrating Ribo-seq and AlphaFold deciphers association patterns between translation velocity and protein structure features" was accepted in iMeta. [Journal Link]
  • 2023.11.14
    Deguchi gives presentation in BSJ 2023. [Conference Link]
  • 2023.11.12
    Bian gives presentation in InCoB 2023. [Conference Link]
  • 2023.11.03
    Wang Yicheng gives presentation in Bioimaging 32. [Conference Link]
  • 2023.10.04
    Our grant proposals for JST GteX was accepted.
  • 2023.09.19
    Our grant proposals for JST CREST and ACT-X were accepted.
  • 2023.09.09
    Jin received Best Poster Presentation in IIBMP 2023. [Conference Link]
  • 2023.09.07
    Bian, Zhang, Wang Yicheng, Jin, Deguchi, Oniduka, Katsuki and Syatila give presentation in IIBMP 2023. [Conference Link]
  • 2023.05.17
    Our grant proposal for NEDO was accepted.
  • 2023.04.21
    Our paper "A multiomics atlas of brown adipose tissue development over time" was accepted in Endocrinology. [Journal Link]
  • 2023.04.01
    Our grant proposal for JSPS KAKENHI was accepted.
  • 2023.04.01
    Iida, Kurumida (Assistant Professor, Kitasato University), Noguchi (JSPS Research Fellow, PD), Dong, Wang, Jin, Deguchi (graduate student, The University of Tokyo) joined our lab. [Member]
  • 2023.02.04
    Our paper "Engineering the substrate specificity of toluene degrading enzyme XylM using biosensor XylS and machine learning" was accepted in ACS Synthetic Biology. [Journal Link]
  • 2023.01.23
    Our paper "Selection of target-binding proteins from the information of weakly enriched phage display libraries by deep sequencing and machine learning" was accepted in mAbs. [Journal Link]
  • 2023.01.20
    Gonzalo Molpeceres (student internship, Spanish National Research Council (CSIC)) joined our lab. [Member]
  • 2022.12.02
    Our paper "EvoOpt: an MSA-guided, fully unsupervised sequence optimization pipeline for protein design" was accepted in Machine Learning in Structural Biology Workshop, NeurIPS2022. [Conference Link] [Paper PDF]
  • 2022.10.13
    We are hiring a postdoc researcher. [JREC-IN Portal Link]
  • 2022.10.03
    Nur Syatila Binti Ab Ghani (postdoc researcher, AIST) joined our lab. [Member]
  • 2022.09.15
    Yamaguchi received Best Poster Presentation in IIBMP 2022. [Conference Link]
  • 2022.09.13
    Yamaguchi, Bian, Shen, Wang and Toki give presentation in IIBMP 2022. [Conference Link]
  • 2022.09.03
    Wang gives presentation in The 31st Annual Meeting of The Bioimaging Society. [Conference Link]
  • 2022.08.22
    Matsushita (student internship, University of Shizuoka) joined our lab. [Member]
  • 2022.08.08
    Katsuki (student internship, The University of Electro-Communications) joined our lab. [Member]
  • 2022.07.29
    Saito received Oxford Journals JSBi Prize 2022. [Link]
  • 2022.05.20
    Saito received JACI Prize for Encouraging Young Researcher 2022. [Link]
  • 2022.05.18
    Our paper "AI and computational chemistry-accelerated development of an alotaketal analogue with conventional PKC selectivity" was accepted in Chemical Communications. [Journal Link]
  • 2022.04.29
    We are hiring a postdoc researcher. [JREC-IN Portal Link]
  • 2022.04.26
    Zhang gives presentation in APBC 2022. [Conference Link]
  • 2022.04.01
    Noguchi (postdoc researcher, AIST) and Oniduka (graduate student, The University of Tokyo) joined our lab. [Member]
  • 2022.02.28
    Our grant proposals for JSPS KAKENHI were accepted in KIBAN-B and KIBAN-A tracks.
  • 2022.02.15
    Toki (student internship, The University of Tokyo) joined our lab. [Member]
  • 2021.12.06
    Our lab web site was renewed!
  • 2021.11.19
    Our paper "Machine-learning-guided library design cycle for directed evolution of enzymes: the effects of training data composition on sequence space exploration" was accepted and selected as Cover Art in ACS Catalysis. [Journal Link] [Cover Art]
  • 2021.10.01
    Bian and Jiang (graduate student, The University of Tokyo) joined our lab. [Member]
  • 2021.09.27
    Yamaguchi, Fukunaga and Oniduka give presentation in IIBMP 2021. [Conference Link]
  • 2021.07.31
    Yamaguchi received Best Talk Award (First Prize) in ISMB / ECCB 2021, Special Session: Representation learning in biology. [Conference Link]
  • 2021.07.25
    Yamaguchi gives presentation in ISMB / ECCB 2021. [Conference Link]
  • 2021.07.22
    Our paper "Machine learning approach for discrimination of genotypes based on bright-field cellular images" was accepted in npj Systems Biology and Applications. [Journal Link]
  • 2021.06.29
    Our paper "Evotuning protocols for Transformer-based variant effect prediction on multi-domain proteins" was accepted in Briefings in Bioinformatics. This is the first paper first-authored by our student! [Journal Link]
  • 2021.06.18
    Yamaguchi received Best Poster Presentation in PSSJ 2021. [Conference Link]
  • 2021.06.16
    Yamaguchi gives presentation in PSSJ 2021. [Conference Link]
  • 2021.05.28
    Our paper "Comparative analysis of the relationship between translation efficiency and sequence features of endogenous proteins in multiple organisms" was accepted in Genomics. [Journal Link]
  • 2021.05.21
    Our grant proposal for AMED was accepted.
  • 2021.04.06
    Our paper "Rational thermostabilisation of four-helix bundle dimeric de novo proteins" was accepted in Scientific Reports. [Journal Link]
  • 2021.04.01
    Shen and Wang (graduate student, The University of Tokyo) joined our lab. [Member]
  • 2021.02.25
    Our paper "Adipose-derived mesenchymal stem cells differentiate into heterogeneous cancer-associated fibroblasts in a stroma-rich xenograft model" was accepted in Scientific Reports. [Journal Link]
Past Topics

北里大学・産総研・東京大学

齋藤研究室

Saito Lab

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